Autoimmune

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ANCA (Anti-Neutrophil Cytoplasmic Abs)

ANCA (Anti-Neutrophil Cytoplasmic Abs)

£69.00
Ex Tax: £69.00
Antineutrophil cytoplasmic antibodies (ANCA) are a group of autoantibodies produced when a person's immune system mistakenly targets and attacks its own white blood cells. Two of the most commonly targeted proteins are myeloperoxidase (MPO) and proteinase 3 (PR3). This results in the production of antibodies to MPO and/or PR3. The ANCA bl...
Anti Mitochondrial Antibodies, AMA

Anti Mitochondrial Antibodies, AMA

£55.00
Ex Tax: £55.00
This test measures whether antimitochondrial antibodies (AMA) are present in the blood. Moderate or high levels of AMA are strongly associated with primary biliary cirrhosis (PBC). PBC is an autoimmune disorder that causes inflammation and scarring of the bile ducts inside the liver, causing continual liver damage and blockage of the bile...
Coombs (Direct Antiglobulin Test)

Coombs (Direct Antiglobulin Test)

£43.00
Ex Tax: £43.00
The direct antiglobulin test (DAT) is used primarily to help determine if the cause of haemolytic anaemia, a condition in which red blood cells (RBCs) are being destroyed more quickly than they can be replaced, is due to antibodies attached to RBCs. This may occur in autoimmune-related haemolytic anaemias, which are caused by a person pro...
DNA (Double Stranded) Antibodies

DNA (Double Stranded) Antibodies

£50.00
Ex Tax: £50.00
While it may be present at a low level with a number of disorders, anti-dsDNA is primarily associated with the autoimmune disorder systemic lupus erythematosus (SLE or Lupus). SLE can affect the kidneys, joints, blood vessels, skin, heart, lungs, and the brain. Symptoms may include joint pain, rashes, fatigue, and kidney dysfunction. SLE ...
Endomysial Antibodies (IgA)

Endomysial Antibodies (IgA)

£53.00
Ex Tax: £53.00
Endomysial Antibodies (IgA) helps in the diagnosis of coeliac disease, and also can help to rule out this diagnosis. These tests detect antibodies that the body creates as part of an immune response to gluten, found in wheat, rye, and barley. These antibodies are involved in inflammation in the gut and damage to the lining of the gut wall...
Extractable Nuclear Antibodies (nRNP, Sm, Ro ,La, Jo1, Scl70)

Extractable Nuclear Antibodies (nRNP, Sm, Ro ,La, Jo1, Scl70)

£55.00
Ex Tax: £55.00
Extractable Nuclear Antigens consist of over 100 different cytoplasmic and nuclear antigens. Autoantibodies to these antigens are associated with particular connective tissue disorders. The six main antigens used in laboratories for detection are Ro, La, Sm, RNP, Scl-70 and Jo1. The pattern of reactivity can help diagnose different autoim...
Intrinsic factor Antibodies (IFA)

Intrinsic factor Antibodies (IFA)

£50.00
Ex Tax: £50.00
Intrinsic factor antibodies are proteins produced by the immune system that are associated with pernicious anemia. This test detects intrinsic factor antibody (IF antibody) circulating in blood. Intrinsic factor is a protein produced by a type of specialized cells that line the stomach wall known as parietal cells. During digestion, st...
Smooth Muscle Antibodies

Smooth Muscle Antibodies

£48.00
Ex Tax: £48.00
The presence of SMA is strongly associated with autoimmune hepatitis. It may also be seen much less commonly in other forms of liver disease such as primary biliary cirrhosis, and in viral infections. Usually higher levels of SMA are seen in autoimmune hepatitis compared with other causes......
Striated/Skeletal Muscle Antibody

Striated/Skeletal Muscle Antibody

£48.00
Ex Tax: £48.00
This test can be used as an aid in the diagnosis of thymoma, especially in patients with onset of myasthenia gravis (MG) younger than 45 years  and as a screening test for MG in older patients, especially when tests for muscle AChR antibodies are negative.....